A normal spring morning cascades into a nightmare world for Mera Stevens as 1.8 billion children simultaneously fall ill and then vanish from the face of the earth. Her son, Jeremy, is one of them. Increased natural disasters, onslaught of disease and other phenomena throws the world into chaos as it balances on the brink of extinction. With communications down, Mera gathers the courage and strength she needs to trek across a dying country in search of a daughter she desperately hopes is still alive. While en route to Seattle, Mera is joined by others on a similar mission. Their travels are not easy. Not only do they have to face nature s roadblocks, they must combat the infected who have become their most deadly obstacle. More than just facing the physical and emotional challenges that test their survival, the group faces a journey that will take them much further than just a search for loved ones in a desolate world.